Neurodermatitis (atopic eczema)

Neurodermatitis is an inflammatory skin disease that occurs in episodes. The most common symptoms are red, scaly skin and severe itching. Sometimes weeping eczema can occur on the skin. This disease occurs in episodes and appears individually depending on the patient's age.

In most cases, the back of the knees, elbows, neck and wrists are affected. However, the face and torso may also be affected.

Neurodermatitis, often referred to as atopic eczema, is one of the so-called atopic diseases. "Atopy" is usually hereditary and often manifests itself in unusually high susceptibility to allergic reactions to substances that are normally harmless. The underlying cause of the disease is the dysregulation (malfunction) of the immune system. This is reflected by an excessive immune response in which a certain group of antibodies, immunoglobulin E (Ig-E), are increasingly produced. Ig-E are, amongst other things, responsible for certain cells releasing substances that cause an inflammatory response.

This quite individually progressing disease is based on a complex combination of genetic factors, immunological changes and environmental influences.

Many classical methods of treatment, such as cortisone or light therapy, can only result in a reduction of symptoms but often go hand in hand with corresponding side effects. However, the immunological cause of the disease remains.

The individual immunotherapy, on the other hand, focuses directly on the dysregulation (malfunction) of the immune system. It can help regulate the immune system with the aim of restoring its balance and to inhibit the excessive release of Ig-E. This can significantly reduce skin irritation up to its permanent disappearance.

The continuously optimised individual immunotherapy has already been applied in thousands of cases involving different forms of autoimmune diseases such as neurodermatitis or allergies. Excellent treatment results can be reached with urexent® therapy, especially in infants and children. The improvement rate is very high and continues long after the end of the treatment.

Together with neurodermatitis and asthma, allergies are a form of atopic diseases­.

Allergies can manifest themselves in different forms. Symptoms range from allergic rhinitis, itchy and burning eyes and allergic asthma and skin reactions to gastrointestinal complaints.

The number of people suffering from allergies, particularly in industrialised countries, has doubled or tripled over the past three decades and is continuously trending upward.

An allergy is an overreaction of the immune system to non-infectious foreign substances (antigens or allergens). The body reacts with various signs of inflammation and the excessive production of antibodies, in particular those of the Ig-E type. People who are effected develop an intolerant reaction to one or more – usually harmless – foreign substances over time, such as flower pollen or dust mites.

The individual immunotherapy directly addresses the cause of the disease. It can have a regulating effect on the misdirected immune system and restore its balance. The excessive production of Ig-E is inhibited, the self-regulation of the immune system is supported and the susceptibility to allergies can decrease.

Bronchial asthma

Bronchial asthma is a chronic inflammatory disease of the airways and is counted among the atopic diseases.

Asthmatics have a permanent inflammation of the bronchial mucosa, resulting in the hypersensitivity of the airways. The result is the swelling of the mucosa and excessive mucus production, which narrows the bronchi. In an acute asthma attack, cramps in the bronchial muscular system occur (bronchospasm), mainly resulting in a decrease in the ability to exhale. Shortness of breath, rapid heart rate and the constant urge to cough may be other symptoms.

Bronchial asthma usually begins in childhood and is one of the most common chronic diseases in this period of life.

Asthma is categorised in two types: allergic and non-allergic asthma. Asthmatics often show links to other allergies – either as the cause in the first type or as the consequence in the second time.

In asthma patients, the immune system is increasingly sensitized to various stimuli. These may be processes within the body, e.g. infections, or stimuli by allergens from outside factors.The increased sensitivity to these triggers causes an increased production of inflammatory mediators, including immunoglobulin E (Ig-E). These interact with the specific antigen and cause the release of allergy and inflammation triggering messenger substances.

The individual immunotherapy initiates the regulation and control of the immune system in this area. By inhibiting the excessive release of antibodies, the bronchi's susceptibility to inflammation can be reduced.

Based on many years of experience with allergies and neurodermatitis, consistent success was achieved – even in patients with asthma or in patients who have more than one forms of the disease.

Psoriasis vulgaris is a chronic inflammatory disease of the skin with redness and severe dandruff. Psoriasis frequently leads to severe itching which can be very distressing for those affected.

Psoriasis is not contagious and it is believed that, amongst other things, a dysregulation of the body's defence system (immune system) plays a role in the pathogenesis. An uncontrolled proliferation of a specific type of immune cell called T-cells in the skin clearly plays a key role. These cells contribute to an increased release of certain messenger substances known as cytokines.

The regulation of the cytokine release cycle appears to be dysfunctional; within the scope of the autoimmune process, a persistent inflammatory response occurs in the skin and also results in a massive proliferation of epidermal cells (keratinocytes). The skin becomes thickened and scaly.

The individual immunotherapy addresses this misdirected process. Its goal is to restore the body's necessary tolerance processes so that its own structures are recognised normally and the balance between inflammatory responses and the healing process is restored and the complexion can be normalized.

Inflammatory bowel diseases

Crohn’s disease and ulcerative colitis are chronic inflammatory bowel diseases. The inflammation usually occurs episodically and is characterized by stomachache and strong, often bloody diarrhea: Oftentimes this results in ulcer formation or constrictions (stenosis).

The number of cases of Crohn’s disease and ulcerative colitis continuously increases, especially in Northern Europe more and more people are affected.

Crohn’s disease can occur in every part of the intestine, but mostly either the end of the small intestine (ileum) or the upper part of the large intestine (colon) is affected. This disease leads to an inflammation of not only the mucosa but all layers of the intestinal wall.

Ulcerative colitis causes an inflammation and ulcer formation within the rectum and colon.

Autoimmune processes, among other things, are discussed as causes for inflammatory bowel diseases. The immune system appears to be directed against the own body and therefore causes a chronic inflammation within the intestine. The percentage of certain antibodies in many cases is increased and the formation of inflammatory mediators is extremely pronounced.

This is the point where the individual immunotherapy comes in. By its regulating effect on the immune system, the excessive formation of antibodies can be reduced and therefore the inflammatory reaction subsides.

Rheumatism refers to discomfort in the musculoskeletal system, which results in severely limited mobility caused by torrential and dragging pain. Rheumatic diseases affect not only bones and joints but also "soft" tissues such as muscles, ligaments or tendons (soft tissue rheumatism). Arthrosis, gout und lupus erythematosus also belong the category of rheumatic diseases.

Rheumatic diseases are divided into inflammatory and degenerative (wear) diseases. The first group belongs to the autoimmune forms of the disease, i. e. the form of disease for which AHIT® therapy is used.

Due to a misdirected immune process, cells that are normally responsible for defending against viruses, bacteria and fungi suddenly attack the body's own healthy tissue. In rheumatoid arthritis, for example, the most common form of inflammatory joint disease, the synovial membrane, is attacked and gradually destroyed.

AHIT® therapy, as an autologous immunotherapy, focuses on regulating the immune system and remedying overreactions and false responses. Through the targeted preparation and manipulation of endogenous substances and their return to the body, the autoimmune reaction can be mitigated and the symptoms reduced.